(2E)-3-(2-甲基苯基)丙烯酰氯合成路线 （共 9 条）
反应条件
thionyl chloride 2 h; Heating;
参考文献
Aitken, R. Alan; Boeters, Christine; Morrison, John J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 17 p. 2625 - 2631
反应条件
thionyl chloride 5 h; Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2786 - 2796
反应条件
1: 87 percent / Na / 3 h / 0 °C 2: 69 percent / 2 M aq. NaOH / 2.5 h / Heating 3: 89 percent / SOCl2 / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 17 p. 2625 - 2631
反应条件
1: 86 percent / piperidine, pyridine / 3.5 h / Heating 2: SOCl2 / dimethylformamide / 16 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 8 p. 1147 - 1156
反应条件
1: 69 percent / 2 M aq. NaOH / 2.5 h / Heating 2: 89 percent / SOCl2 / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 17 p. 2625 - 2631
反应条件
1: 1.) BuLi / 1.) THF, hexane, r.t., 15 min, 2.) 8 h 2: 15 percent / 0 h / 900 °C / 0 - 0.1 Torr View Scheme
参考文献
Aitken, R. Alan; Boeters, Christine; Morrison, John J.
Tetrahedron Letters, 1995 , vol. 36, # 8 p. 1303 - 1306
反应条件
1: 1.) BuLi / 1.) THF, hexane, r.t., 15 min, 2.) 8 h 2: 9 percent / 0 h / 900 °C / 0 - 0.1 Torr View Scheme
参考文献
Aitken, R. Alan; Boeters, Christine; Morrison, John J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 17 p. 2625 - 2631
反应条件
1: Et3N / 20 °C
2: NBS; AIBN / CCl4 / 2 h / Heating
View Scheme
参考文献
Ma, Zhongze; Lee, David Y.W.
Tetrahedron Letters, 2004 , vol. 45, # 36 p. 6721 - 6723
反应条件
1: 1.) BuLi / 1.) THF, hexane, r.t., 15 min, 2.) 8 h
2: 25 percent / 0 h / 900 °C / 0 - 0.1 Torr
View Scheme
参考文献
Aitken, R. Alan; Boeters, Christine; Morrison, John J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 17 p. 2625 - 2631
