反应条件
1: 4-(dimethylamino)pyridine, dicyclohexylcarbodiimide / CH2Cl2 / 3 h 2: p-TsOH / acetonitrile / 1.75 h / Heating 3: DCC, 1-hydroxybenzotriazole hydrate, diisopropylethylamine / tetrahydrofuran / 1.) 0 deg C, 1.5 h, 2.) room temperature, 18 h 4: tetrabutylammonium fluoride trihydrate / dimethylformamide / 15 h View Scheme
参考文献
Krapcho; Turk; Cushman; Powell; DeForrest; Spitzmiller; Karanewsky; Duggan; Rovnvak; Schwartz; Natarajan; Godfrey; Ryono; Neubeck; Atwa; Petrillo Jr.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1148 - 1160
