乙基4-(2-氯苯基)-3-氧代丁酸酯合成路线 （共 3 条）
反应条件
triethylamine; magnesium chloride
1.) CH3CN, RT, 2 h, 2.) CH3CN, a) RT, overnight, b) reflux, 2 h; Yield givenMultistep reaction;
参考文献
Mai, Antonello; Artico, Marino; Sbardella, Gianluca; Massa, Silvio; Novellino, Ettore; Greco, Giovanni; Loi, Anna Giulia; Tramontane, Enzo; Marongiu, Maria Elena; La Colla, Paolo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 619 - 627
反应条件
1: tetrahydrofuran / 16 h / 0 - 20 °C
2: tetrahydrofuran; acetonitrile / 16 h / Ambient temperature
View Scheme
参考文献
Augelli-Szafran, Corinne E.; Horwell, David C.; Kneen, Clare; Ortwine, Daniel F.; Pritchard, Martyn C.; Purchase, Terri S.; Roth, Bruce D.; Trivedi, Bharat K.; Hill, David; Suman-Chauhan, Nirmala; Webdale, Louise
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 10 p. 1733 - 1745
反应条件
in tetrahydrofuran; acetonitrile
16 h; Ambient temperature; Yield given;
参考文献
Augelli-Szafran, Corinne E.; Horwell, David C.; Kneen, Clare; Ortwine, Daniel F.; Pritchard, Martyn C.; Purchase, Terri S.; Roth, Bruce D.; Trivedi, Bharat K.; Hill, David; Suman-Chauhan, Nirmala; Webdale, Louise
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 10 p. 1733 - 1745
