N-[(2E)-3-(2-呋喃基)-2-丙烯酰]-L-苯丙氨酰-L-苯丙氨酸合成路线 （共 8 条）
反应条件
carboxypeptidase from yeast (CPase-Y) in acetonitrile
T=30°C; P=750060 Torr; 3 h; pH=9.5;
参考文献
Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Morikawa, Yoshio; Ito, Takanobu; et al.
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 2 p. 514 - 518
反应条件
carboxypeptidase from yeast (CPase-Y) in N,N-dimethyl-formamide
T=30°C; P=1500120 Torr; 3 h; pH=8.0;
参考文献
Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Morikawa, Yoshio; Ito, Takanobu; et al.
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 2 p. 514 - 518
反应条件
carboxypeptidase from yeast (CPase-Y) in acetonitrile
T=30°C; P=750.06 Torr; 3 h; pH=9.5;
参考文献
Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Morikawa, Yoshio; Ito, Takanobu; et al.
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 2 p. 514 - 518
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water
T=20°C; 6 h;
参考文献
Tanco, Sebastian; Zhang, Xin; Morano, Cain; Aviles, Francesc Xavier; Lorenzo, Julia; Fricker, Lloyd D.
Journal of Biological Chemistry, 2010 , vol. 285, # 24 p. 18385 - 18396
反应条件
carboxypeptidase W
T=25°C; pH = 7.5; various pH-s, enzymes; Product distribution;
参考文献
Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Fukuda, Mitsuhiro
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 4 p. 1399 - 1402
反应条件
1: dicyclohexyl-carbodiimide / 1,4-dioxane; N,N-dimethyl-formamide / 16 h / 4 °C
2: sodium hydrogencarbonate / 1,4-dioxane; water / 6 h / 20 °C
View Scheme
参考文献
Tanco, Sebastian; Zhang, Xin; Morano, Cain; Aviles, Francesc Xavier; Lorenzo, Julia; Fricker, Lloyd D.
Journal of Biological Chemistry, 2010 , vol. 285, # 24 p. 18385 - 18396
反应条件
N,N-dimethyl-formamide
T=37°C; aminolysis by carboxypeptidase Y, pH = 8.0;
参考文献
Shima, Hiroshi; Fukuda, Mitsuhiro; Tanabe, Kazuo; Ito, Takanobu; Kunugi, Shigeru
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 4 p. 1403 - 1406
反应条件
sodium chloride; 0.6 μM carboxypeptidase Y in N,N-dimethyl-formamide
T=30°C; 3 h; pH=8.0, sealed polypropylene bottle; other amino acid amide; Product distribution;
参考文献
Kunugi, S.; Tanabe, K.; Fukuda, M.; Makimoto, S.; Taniguchi, Y.
Journal of the Chemical Society, Chemical Communications, 1987 , # 18 p. 1335 - 1336
