2-BOC-氨基噻唑-4-羧酸合成路线 （共 3 条）
反应条件
1: With lithium hydroxide in tetrahydrofuran; water 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
Chu, Xin-Jie; Fotouhi, Nader; Huby, Nicholas J.S.; Kong, Norman; McDermott, Lee Apostle; Moliterni, John; Zhang, Zhuming
Patent: US2006/41146 A1, 2006 ;
Location in patent: Page/Page column 15 ;
US 20060041146 A1
反应条件
1: With lithium hydroxide in tetrahydrofuran; water T=20°C; 2: With hydrogenchloride in water
参考文献
Goodnow,, Robert Alan; Huby, Nicholas J.S.; Kong, Norman; McDermott, Lee Apostle; Moliterni, John Anthony; Zhang, Zhuming
Patent: US2006/63814 A1, 2006 ;
Location in patent: Page/Page column 61 ;
US 20060063814 A1
反应条件
1: 57 percent / tetrahydrofuran / 36 h / Heating 2: 92 percent / aq. LiOH / tetrahydrofuran; dimethylformamide / 2 h / 60 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 27 p. 6382 - 6394
