1: hydrogenchloride / 4 h / |Reflux 2: water / tert-butyl methyl ether / 5 h / 45 °C / |Enzymatic reaction View Scheme

water in tert-butyl methyl ether T=60°C; 26 h; Enzymatic reaction; Catalytic behavior; Reagent/catalystSolventpH-valueTime; Overall yield = 51 percentChromat.; enantioselective reaction;