1: H2NNH2*H2O / tetrahydrofuran / 20 h / 50 °C 2: 6.41 g / tetrabutylammonium fluoride trihydrate / tetrahydrofuran / 2 h / 25 °C 3: 67 percent / CuSO4*5H2O / H2O / 0.75 h / Heating View Scheme

1: 2,4,6-Trichloropyridine With n-butyllithium in tetrahydrofuran; hexane T=-75°C; 0.75 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane

1.1: BuLi / tetrahydrofuran; hexane / 0.75 h / -75 °C 1.2: 64 percent / I2 / tetrahydrofuran; hexane / 0.25 h / -75 °C 2.1: isobutylmagnesium chloride / tetrahydrofuran / 0.75 h / 0 °C 2.2: 94 percent / N-chlorosuccinimide / tetrahydrofuran / 0.75 h 3.1: BuLi / tetrahydrofuran; hexane / 0.75 h / -75 °C 3.2: 92 percent / tetrahydrofuran; hexane View Scheme

1.1: isobutylmagnesium chloride / tetrahydrofuran / 0.75 h / 0 °C 1.2: 94 percent / N-chlorosuccinimide / tetrahydrofuran / 0.75 h 2.1: BuLi / tetrahydrofuran; hexane / 0.75 h / -75 °C 2.2: 92 percent / tetrahydrofuran; hexane View Scheme

1: H2NNH2*H2O / tetrahydrofuran / 20 h / 50 °C 2: 6.41 g / tetrabutylammonium fluoride trihydrate / tetrahydrofuran / 2 h / 25 °C 3: 67 percent / CuSO4*5H2O / H2O / 0.75 h / Heating 4: 88 percent / H2O / 20 h / 50 °C View Scheme