5-甲基-2'-脱氧胞苷合成路线 (共 29 条)
参考文献
Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio
Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780
反应条件
ammonium hydroxide in 1,4-dioxane Ambient temperature;
参考文献
Sung, Wing L.
Journal of the Chemical Society, Chemical Communications, 1981 , # 20 p. 1089
反应条件
pyridine; pyridinium poly(hydrogen fluoride) in ethyl acetate
参考文献
Muenzel, Martin; Globisch, Daniel; Brueckl, Tobias; Wagner, Mirko; Welzmiller, Veronika; Michalakis, Stylianos; Mueller, Markus; Biel, Martin; Carell, Thomas
Angewandte Chemie - International Edition, 2010 , vol. 49, # 31 p. 5375 - 5377
反应条件
1: Et3N / CH2Cl2 / 0.5 h 2: acetonitrile / 2 h / Ambient temperature 3: NH3 / tetrahydrofuran / 72 h / 70 °C View Scheme
参考文献
Nucleosides and Nucleotides, , vol. 15, # 4 p. 907 - 921
参考文献
Journal of the American Chemical Society, , vol. 81, p. 178,187
Biochemical Preparations, , vol. 10, p. 98,102
反应条件
ethylenediaminetetraacetic acid; dihydrogen peroxide; iron(II) sulfate; ascorbic acid powder in aq. phosphate buffer T=37°C; pH=7.3;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 1 p. 260 - 265
反应条件
ethylenediaminetetraacetic acid; dihydrogen peroxide; iron(II) sulfate; ascorbic acid powder in aq. phosphate buffer T=37°C; pH=7.3; 3 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 1 p. 260 - 265
反应条件
1: aqueous pyridine; P2S5 2: ethanol; NH3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 81, p. 178,187
反应条件
1: 77 percent / dimethyldioxirane, NH3 / acetone; CH2Cl2 / 25 °C 2: 85 percent / 2N methanol. NH3 / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 52, # 19 p. 6759 - 6780
反应条件
dichloro-acetic acid in dichloromethane
参考文献
Nucleosides and Nucleotides, , vol. 16, # 7-9 p. 1271 - 1278