5-甲基-2'-脱氧胞苷合成路线 （共 29 条）
反应条件
1: oxygen / aq. buffer / 60 °C / pH 7.4 2: aq. buffer / 80 °C / pH 7.4 3: aq. buffer / 60 °C / pH 7.4 View Scheme
参考文献
Schiesser, Stefan; Pfaffeneder, Toni; Sadeghian, Keyarash; Hackner, Benjamin; Steigenberger, Barbara; Schroeder, Arne S.; Steinbacher, Jessica; Kashiwazaki, Gengo; Hoefner, Georg; Wanner, Klaus T.; Ochsenfeld, Christian; Carell, Thomas
Journal of the American Chemical Society, 2013 , vol. 135, # 39 p. 14593 - 14599
反应条件
sodium peroxodisulphate in water T=75°C; 4 h; sodium phosphate buffer pH 7.0;
参考文献
Chemistry Letters, , p. 1591 - 1594
反应条件
sodium peroxodisulphate in water T=75°C; 3 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 67, # 8 p. 2257 - 2264
反应条件
1: 5-Methyl-2'-deoxycytidine; benzoic acid anhydride in DMF (N,N-dimethyl-formamide)
T=40°C; 5 h;
2: 4,4'-dimethoxytriphenylmethyl chloride With pyridine in DMF (N,N-dimethyl-formamide)
T=10°C; 15 h;
3: With sodium hydroxide; sodium hydrogencarbonate
Product distribution / selectivity; more than 3 stages;
参考文献
MITSUI CHEMICALS, INC.
Patent: US2005/192433 A1, 2005 ;
Location in patent: Page/Page column 6 ;
反应条件
1: 13 percent / air, 2-methyl-1,4-naphthoquinone / H2O / 1 h / Ambient temperature; Irradiation
2: 74 percent / NaBH4 / methanol / Ambient temperature
View Scheme
参考文献
Schiesser, Stefan; Pfaffeneder, Toni; Sadeghian, Keyarash; Hackner, Benjamin; Steigenberger, Barbara; Schroeder, Arne S.; Steinbacher, Jessica; Kashiwazaki, Gengo; Hoefner, Georg; Wanner, Klaus T.; Ochsenfeld, Christian; Carell, Thomas
Journal of the American Chemical Society, 2013 , vol. 135, # 39 p. 14593 - 14599
反应条件
sodium peroxodisulphate in water
T=75°C; 4 h; sodium phosphate buffer pH 7.0;
参考文献
Itahara, Toshio
Chemistry Letters, 1991 , p. 1591 - 1594
反应条件
9,10-anthraquinone-2-sulfonate in water
T=0°C; pH=7; 1 h; UV-irradiationaq.sodium cacodylate buffer; Mechanism; TimeSolvent;
参考文献
Yamada, Hisatsugu; Kitauchi, Yuya; Tanabe, Kazuhito; Ito, Takeo; Nishimoto, Sei-Ichi
Chemistry - A European Journal, 2011 , vol. 17, # 7 p. 2225 - 2235
反应条件
sodium peroxodisulphate in water
T=75°C; 3 h;
参考文献
Itahara; Yoshitake; Koga; Nishino
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 8 p. 2257 - 2264
反应条件
1: oxygen / aq. buffer / 60 °C / pH 7.4
2: air / aq. buffer / 60 °C / pH 7.4
3: aq. buffer / 60 °C / pH 7.4
View Scheme
参考文献
Schiesser, Stefan; Pfaffeneder, Toni; Sadeghian, Keyarash; Hackner, Benjamin; Steigenberger, Barbara; Schroeder, Arne S.; Steinbacher, Jessica; Kashiwazaki, Gengo; Hoefner, Georg; Wanner, Klaus T.; Ochsenfeld, Christian; Carell, Thomas
Journal of the American Chemical Society, 2013 , vol. 135, # 39 p. 14593 - 14599
