4-苯并噁唑-2-苯甲腈合成路线 （共 22 条）
反应条件
1: DBU / PdCl2(PPh3)2, PPh3 / N,N-dimethyl-acetamide / 0.5 h / 120 °C / 4654.3 Torr
2: conc. HCl / N,N-dimethyl-acetamide / 16 h / Heating
View Scheme
参考文献
Perry, Robert J.; Wilson, B. David; Miller, Richard J.
Journal of Organic Chemistry, 1992 , vol. 57, # 10 p. 2883 - 2887
反应条件
PdCl(C3H5)(dppb); caesium carbonate in CPME
T=130°C; 44 h; Inert atmosphere;
参考文献
Beydoun, Kassem; Doucet, Henri
ChemSusChem, 2011 , vol. 4, # 4 p. 526 - 534
反应条件
copper(l) iodide; oxygen; palladium diacetate; potassium carbonate in 1,4-dioxane
T=120°C; 48 h; Sealed tube;
参考文献
Zhang, Manli; Zhang, Shouhui; Liu, Miaochang; Cheng, Jiang
Chemical Communications, 2011 , vol. 47, # 41 p. 11522 - 11524
反应条件
iodine; N,N-dimethyl-formamide in chlorobenzene
T=130°C;
参考文献
Teo, Yew Chin; Riduan, Siti Nurhanna; Zhang, Yugen
Green Chemistry, 2013 , vol. 15, # 9 p. 2365 - 2368
反应条件
1: 98 percent / tetrahydrofuran / 24 h / 20 °C
2: 98 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
di-tert-butyl peroxide; FeBr2
T=110°C; Inert atmosphere;
参考文献
Gu, Lijun; Jin, Cheng; Guo, Junming; Zhang, Lizhu; Wang, Wei
Chemical Communications, 2013 , vol. 49, # 93 p. 10968 - 10970
反应条件
palladium dichloride in chlorobenzene
Reflux;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
1: 98 percent / tetrahydrofuran / 24 h / 20 °C
2: 98 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
1: 98 percent / tetrahydrofuran / 24 h / 20 °C
2: 93 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran
18 h; Heating;
参考文献
Bayh, Omar; Awad, Hacan; Mongin, Florence; Hoarau, Christophe; Bischoff, Laurent; Trecourt, Francois; Queguiner, Guy; Marsais, Francis; Blanco, Fernando; Abarca, Belen; Ballesteros, Rafael
Journal of Organic Chemistry, 2005 , vol. 70, # 13 p. 5190 - 5196
