(3,4-二氨基苯基)(2-噻吩基)甲酮合成路线 （共 3 条）
反应条件
SnCl2·2H2O in ethanol; water
T=80°C; 12 h; Inert atmosphere;
参考文献
Park, Hwangseo; Hong, Seunghee; Kim, Jinhee; Hong, Sungwoo
Journal of the American Chemical Society, 2013 , vol. 135, # 22 p. 8227 - 8237
反应条件
1: thionyl chloride / 5 h / 60 °C / |Inert atmosphere
2: AlCl3, aluminium chloride / dichloromethane / 5 h / 60 °C / |Inert atmosphere
3: SnCl2·2H2O; water / ethanol / 12 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Hong, Seunghee; Kim, Jinhee; Yun, Sun-Mi; Lee, Hyunseung; Park, Yoonsu; Hong, Soon-Sun; Hong, Sungwoo
Journal of Medicinal Chemistry, 2013 , vol. 56, # 9 p. 3531 - 3545
反应条件
1: AlCl3, aluminium chloride / dichloromethane / 5 h / 60 °C / |Inert atmosphere
2: SnCl2·2H2O; water / ethanol / 12 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Hong, Seunghee; Kim, Jinhee; Yun, Sun-Mi; Lee, Hyunseung; Park, Yoonsu; Hong, Soon-Sun; Hong, Sungwoo
Journal of Medicinal Chemistry, 2013 , vol. 56, # 9 p. 3531 - 3545
