chromium(VI) oxide; acetic acid in water T=20°C; 12 h;

1: With n-butyllithium in hexane T=40°C; 1 h; Inert atmosphere; 2: With 1,2-dibromo-1,1,2,2-tetrachloroethane in hexane T=25°C; 4 h; Inert atmosphere;

1: 41 percent / CrO3; AcOH / H2O / 12 h / 20 °C 2: 62 percent / diethyl ether / 140 h / 40 °C 3: 40 percent / K3PO4; Pd(dba)2; bis[2-(diphenylphosphino)phenyl] ether / toluene / 24 h / 110 °C View Scheme