4-(6-羟基己氧基)苯甲酸合成路线 （共 18 条）
反应条件
in isobutyramide T=25 - 30°C; 1.25 h; Product distribution / selectivity;
参考文献
HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH
Patent: WO2005/30696 A1, 2005 ;
Location in patent: Page/Page column 11-12 ;
反应条件
toluene-4-sulfonic acid in benzene
参考文献
Lacoudre, Nelly; Borgne, Alain le; Spassky, Nicolas; Vairon, Jean-Pierre; Barny, Pierre le; et al.
Molecular Crystals and Liquid Crystals (1969-1991), 1988 , vol. 155, p. 113 - 128
反应条件
1: N,N-dimethyl-aniline / 1,4-dioxane / 3 h / 60 °C 2: dicyclohexyl-carbodiimide; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 48 h View Scheme
参考文献
Chen, Xingwu; Wang, Ling; Chen, Yinjie; Li, Chenyue; Hou, Guoyan; Liu, Xin; Zhang, Xiaoguang; He, Wanli; Yang, Huai
Chemical Communications, 2014 , vol. 50, # 6 p. 691 - 694
反应条件
1: With sodium hydroxide; water
T=90°C; 8 h;
2: With hydrogenchloride in water
pH=3 - 5;
参考文献
Southwest Research Institute
Patent: US7098359 B2, 2006 ;
Location in patent: Page/Page column 9; 27 ;
反应条件
1: With potassium hydroxide in methanol
T=50°C; 12 h;
2: With hydrogenchloride in water
参考文献
Ramkumar; Amala Rose; Ramakrishnan
Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 14 p. 3200 - 3209
反应条件
1: With potassium carbonate in DMF (N,N-dimethyl-formamide)
T=100°C; 4 h;
2: With potassium hydroxide in water
3 h; Heating / reflux;
参考文献
Nippon Oil Corporation
Patent: EP1405850 A1, 2004 ;
Location in patent: Page 15 ;
反应条件
potassium hydroxide in water
T=60°C; 6 h;
参考文献
Chen, Xingwu; Wang, Ling; Chen, Yinjie; Li, Chenyue; Hou, Guoyan; Liu, Xin; Zhang, Xiaoguang; He, Wanli; Yang, Huai
Chemical Communications, 2014 , vol. 50, # 6 p. 691 - 694
反应条件
potassium hydroxide; potassium iodide in ethanol; water
20 h; Heating;
参考文献
Cowie, J. M. G.; Hunter, H. W.
Canadian Journal of Chemistry, 1995 , vol. 73, p. 1811 - 1817
反应条件
potassium hydroxide in ethanol; water
参考文献
Lacoudre, Nelly; Borgne, Alain le; Spassky, Nicolas; Vairon, Jean-Pierre; Barny, Pierre le; et al.
Molecular Crystals and Liquid Crystals (1969-1991), 1988 , vol. 155, p. 113 - 128
反应条件
1: K2CO3 / butan-2-one
2: aq. KOH / ethanol
View Scheme
参考文献
Aldred, Matthew P.; Vlachos, Panos; Contoret, Adam E. A.; Farrar, Simon R.; Chung-Tsoi; Mansoor, Bassam; Woon, Kai L.; Hudson, Robert; Kelly, Stephen M.; O'Neill, Mary
Journal of Materials Chemistry, 2005 , vol. 15, # 31 p. 3208 - 3213
