N-(4-乙酰苯)-2,5-二甲基吡咯合成路线 (共 4 条)
反应条件
acetic acid Paal-Knorr Pyrrole Synthesis; 0.5 h; Reflux;
参考文献
More, Uttam A.; Joshi, Shrinivas D.; Aminabhavi, Tejraj M.; Gadad, Andanappa K.; Nadagouda, Mallikarjuna N.; Kulkarni, Venkatrao H.
European Journal of Medicinal Chemistry, 2014 , vol. 71, p. 199 - 218
反应条件
n-butyllithium in diethyl ether; hexane 1.) -20 deg C, 50 min, 2.) - 20 deg C, 1 h, 3.) 2 h;
参考文献
Bruekelman, Stephen P.; Leach, (Miss) Susan E.; Meakins, G. Denis; Tirel, Malcolm D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2801 - 2807
反应条件
1: 96 percent / AcOH / benzene / 4 h / Heating 2: 92 percent / n-BuLi / hexane; diethyl ether / 1.) -20 deg C, 50 min, 2.) - 20 deg C, 1 h, 3.) 2 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2801 - 2807
反应条件
1: 96 percent / AcOH / benzene / 4 h / Heating 2: 92 percent / n-BuLi / hexane; diethyl ether / 1.) -20 deg C, 50 min, 2.) - 20 deg C, 1 h, 3.) 2 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2801 - 2807