5-氨基-2-(4-苯胺基)苯并呋喃合成路线 （共 5 条）
反应条件
hydrogen; palladium dihydroxide; barium sulfate in N,N-dimethyl-formamide
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
反应条件
N-ethyl-N,N-diisopropylamine in 1,4-dioxane
参考文献
SHARP KABUSHIKI KAISHA
Patent: EP780363 A1, 1997 ;
反应条件
1: 1) C2H5ONa; 2) KI / 1) ethanol, 30 min, 80 deg C, DMF; 2) DMF, 2 h, reflux
2: 80 percent / NaOCH3 / dimethylformamide; methanol / 0.5 h / Heating
3: 71 percent / H2 / Pd(OH)2/BaSO4 / dimethylformamide
View Scheme
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
反应条件
1: 80 percent / NaOCH3 / dimethylformamide; methanol / 0.5 h / Heating
2: 71 percent / H2 / Pd(OH)2/BaSO4 / dimethylformamide
View Scheme
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
反应条件
1: 1) C2H5ONa; 2) KI / 1) ethanol, 30 min, 80 deg C, DMF; 2) DMF, 2 h, reflux
2: 80 percent / NaOCH3 / dimethylformamide; methanol / 0.5 h / Heating
3: 71 percent / H2 / Pd(OH)2/BaSO4 / dimethylformamide
View Scheme
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
