4,4,4-三氟丁胺盐酸盐合成路线 （共 4 条）
反应条件
1: With Boc2NH; triphenylphosphine; diethylazodicarboxylate in toluene T=20 - 25°C; 18 h; 2: With trifluoroacetic acid T=0 - 20°C; 24 h;
参考文献
WO2004/111003 A1, ;
Page 54-55 ;
WO 2004/111003 A1
反应条件
hydrogenchloride in diethyl ether
参考文献
US2008/15237 A1, ;
Page/Page column 30 ;
US 20080015237 A1
反应条件
sodium nitrite in perchloric acid pH: 3.5; Product distributionMechanism;
参考文献
Gassen, Karl-Rudolf; Kirmse, Wolfgang
Chemische Berichte, 1986 , vol. 119, # 7 p. 2233 - 2248
反应条件
sodium nitrite in perchloric acid pH: 3.5; Product distributionMechanism;
参考文献
Chemische Berichte, , vol. 119, # 7 p. 2233 - 2248
