3-(4-哌啶基)-1,2-苯并异恶唑N-氨基甲酸苯基酯合成路线 （共 5 条）
反应条件
potassium hydroxide in ethanol 16 h; Heating;
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
in toluene
16 h; Heating;
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
2: H2NOH*HCl, 85percent aq. KOH / 2-ethoxy-ethanol / 5 h / Heating
3: 78 percent / toluene / 16 h / Heating
View Scheme
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
1: H2NOH*HCl, 85percent aq. KOH / 2-ethoxy-ethanol / 5 h / Heating
2: 78 percent / toluene / 16 h / Heating
View Scheme
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
2: H2NOH*HCl, 85percent aq. KOH / 2-ethoxy-ethanol / 5 h / Heating
3: 78 percent / toluene / 16 h / Heating
View Scheme
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
