1: iso-butyronitrile With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.333333 h;
2: 4-bromo-but-1-ene in tetrahydrofuran
T=-78 - 20°C;
参考文献
Burrell, Adam J. M.; Coldham, Iain; Watson, Luke; Oram, Niall; Pilgram, Christopher D.; Martin, Nathaniel G.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2290 - 2300
1: With diisobutylaluminium hydride in hexane; dichloromethane
T=-78°C; 1.5 h;
2: With hydrogenchloride; water in hexane; dichloromethane
T=-78 - 20°C;
参考文献
Burrell, Adam J. M.; Coldham, Iain; Watson, Luke; Oram, Niall; Pilgram, Christopher D.; Martin, Nathaniel G.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2290 - 2300
