反应条件
1: diethyl malonate With sodium hydride in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: 4-(phenylmethoxy)benzyl chloride in N,N-dimethyl-formamide
3 h;
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031