chromium(VI) oxide in acetone 3 h; Ambient temperature;

1: 1.) LiN(iPr)2 / 1.) THF, -70 deg C, 4 h, 2.) THF, -70 deg C, 1 h 2: 95 percent / CrO3 / acetone / 3 h / Ambient temperature View Scheme

1: tetrahydrofuran / 0 - 5 °C 2: chromium(VI) oxide / acetone / -70 - 25 °C View Scheme

1.1: trans-PdCl2(PPh3)2; triethylamine / 0.25 h / 20 °C / Inert atmosphere 1.2: 1 h / 80 °C / Inert atmosphere 2.1: ammonia; silver trifluoromethanesulfonate / methanol / 1 h / 120 °C / Microwave irradiation; sealed tube View Scheme