4-(环丙基甲基氨基)-3-硝基吡啶合成路线 （共 4 条）
反应条件
palladium on carbon; hydrogen in ethanol T=20°C; P=2585.81 Torr; 60 h;
参考文献
Ryckmans, Thomas; Edwards, Martin P.; Horne, Val A.; Correia, Ana Monica; Owen, Dafydd R.; Thompson, Lisa R.; Tran, Isabelle; Tutt, Michelle F.; Young, Tim
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4406 - 4409
反应条件
in ethanol
T=85°C; 48 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/11700 A1, 2005 ;
Location in patent: Page/Page column 82 ;
WO 2005/011700 A1
反应条件
in ethanol
T=80°C; 12 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/46678 A1, 2005 ;
Location in patent: Page/Page column 74 ;
WO 2005/046678 A1
反应条件
triethylamine in toluene
T=110°C; 16 h;
参考文献
Ryckmans, Thomas; Edwards, Martin P.; Horne, Val A.; Correia, Ana Monica; Owen, Dafydd R.; Thompson, Lisa R.; Tran, Isabelle; Tutt, Michelle F.; Young, Tim
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4406 - 4409
