4-溴吡啶-2-胺合成路线

参考文献

Sunose, Mihiro; Bell, Kathryn; Ellard, Katie; Bergamini, Giovanna; Neubauer, Gitte; Werner, Thilo; Ramsden, Nigel
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4613 - 4618

107-20-0一氯乙醛+

84249-14-94-溴吡啶-2-胺

808744-34-57-溴咪唑并[1,2-a]吡啶

参考文献

ARRAY BIOPHARMA INC.
Patent: WO2008/124323 A1, 2008 ;
Location in patent: Page/Page column 68 ;
WO 2008/124323 A1

84249-14-94-溴吡啶-2-胺+

24424-99-5二碳酸二叔丁酯

207799-10-84-溴吡啶-2-氨基甲酸叔丁酯

参考文献

CROWN BIOSCIENCE INC. (TAICANG); ZHANG, Deyi; ZHANG, Ruihao; ZHONG, Boyu; SHIH, Chuan
Patent: WO2014/418 A1, 2014 ;
Location in patent: Page/Page column 30; 31 ;

110-91-8吗啉+

84249-14-94-溴吡啶-2-胺

722549-98-62-氨基-4-(4-吗啉基)吡啶

参考文献

AMGEN INC.; DRANSFIELD, Paul, John; GONZALEZ LOPEZ DE TURISO, Felix; KOHN, Todd, J.; PATTAROPONG, Vatee; SIMARD, Jillian, L.
Patent: WO2012/3283 A1, 2012 ;
Location in patent: Page/Page column 92 ;
WO 2012/003283 A1

84249-14-94-溴吡啶-2-胺+

70-11-12-溴苯乙酮

1018814-40-87-溴-2-苯基咪唑并[1,2-a]吡啶

参考文献

S*BIO PTE LTD
Patent: WO2006/101455 A1, 2006 ;
Location in patent: Page/Page column 80 ;

84249-14-94-溴吡啶-2-胺

1019021-93-27-溴-咪唑并[1,2-a]吡啶-3-羧酸

参考文献

WO2011/79076 A1, ;

84249-14-94-溴吡啶-2-胺

1053655-66-57-溴-[1,2,4]噻唑并[1,5-a]吡啶

参考文献

Katoh, Issei; Aoki, Toshiaki; Suzuki, Hideyuki; Utsunomiya, Iwao; Kuroda, Norikazu; Iwaki, Tsutomu
Patent: US2011/98471 A1, 2011 ;

84249-14-94-溴吡啶-2-胺

1019023-07-47-溴-2-(氯甲基)-咪唑并[1,2-a]吡啶

参考文献

US2013/237502 A1, ;

84249-14-94-溴吡啶-2-胺+

100-47-0苯甲腈

1380331-12-3

参考文献

F. HOFFMANN-LA ROCHE AG; BARTELS, Bjoern; FANTASIA, Serena Maria; FLOHR, Alexander; PUENTENER, Kurt; WANG, Shaoning
Patent: WO2013/117610 A1, 2013 ;
Location in patent: Page/Page column 6 - 12 ;

参考文献

F. HOFFMANN-LA ROCHE AG; BARTELS, Bjoern; FANTASIA, Serena Maria; FLOHR, Alexander; PUENTENER, Kurt; WANG, Shaoning
Patent: WO2013/117610 A1, 2013 ;
Location in patent: Page/Page column 6 ;