4-溴吡啶-2-胺合成路线

参考文献

Flohr, Alexander; Gobbi, Luca; Groebke Zbinden, Katrin; Koerner, Matthias; Peters, Jens-Uwe
Patent: US2012/142665 A1, 2012 ;

Title/Abstract Full Text Show Details
F. HOFFMANN-LA ROCHE AG; FLOHR, Alexander; GOBBI, Luca; GROEBKE ZBINDEN, Katrin; KOERNER, Matthias; PETERS, Jens-Uwe
Patent: WO2012/76430 A1, 2012 ;
WO 2012/076430 A1

84249-14-94-溴吡啶-2-胺

1380331-36-1

参考文献

Flohr, Alexander; Gobbi, Luca; Groebke Zbinden, Katrin; Koerner, Matthias; Peters, Jens-Uwe
Patent: US2012/142665 A1, 2012 ;

Title/Abstract Full Text Show Details
F. HOFFMANN-LA ROCHE AG; FLOHR, Alexander; GOBBI, Luca; GROEBKE ZBINDEN, Katrin; KOERNER, Matthias; PETERS, Jens-Uwe
Patent: WO2012/76430 A1, 2012 ;
WO 2012/076430 A1

84249-14-94-溴吡啶-2-胺

1380331-40-7

参考文献

Flohr, Alexander; Gobbi, Luca; Groebke Zbinden, Katrin; Koerner, Matthias; Peters, Jens-Uwe
Patent: US2012/142665 A1, 2012 ;

Title/Abstract Full Text Show Details
F. HOFFMANN-LA ROCHE AG; FLOHR, Alexander; GOBBI, Luca; GROEBKE ZBINDEN, Katrin; KOERNER, Matthias; PETERS, Jens-Uwe
Patent: WO2012/76430 A1, 2012 ;
WO 2012/076430 A1

84249-14-94-溴吡啶-2-胺

214342-63-94-溴-1-甲基吡啶-2-酮

参考文献

WASHINGTON UNIVERSITY
Patent: US2011/311447 A1, 2011 ;

84249-14-94-溴吡啶-2-胺+

74-88-4甲基碘

214342-63-94-溴-1-甲基吡啶-2-酮

参考文献

Li, Junfeng; Zhang, Xiang; Zhang, Zhanbin; Padakanti, Prashanth K.; Jin, Hongjun; Cui, Jinquan; Li, Aixiao; Zeng, Dexing; Rath, Nigam P.; Flores, Hubert; Perlmutter, Joel S.; Parsons, Stanley M.; Tu, Zhude
Journal of Medicinal Chemistry, 2013 , vol. 56, # 15 p. 6216 - 6233

84249-14-94-溴吡啶-2-胺

1187449-01-94-溴-5-氯-2-吡啶胺

参考文献

WO2009/112473 A1, ;

Page/Page column 68-69 ;
WO 2009/112473 A1

84249-14-94-溴吡啶-2-胺+

70-23-53-溴丙酮酸乙酯

1187236-18-57-溴咪唑并[1,2-a]吡啶-2-羧酸乙酯

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ABEYWARDANE, Asitha; BRUNETTE, Steven Richard; BURKE, Michael Jason; KIRRANE, Thomas Martin, Jr.; MAN, Chuk Chui; MARSHALL, Daniel Richard; PADYANA, Anil Kumar; RAZAVI, Hossein; SIBLEY, Robert; SMITH KEENAN, Lana Louise; SNOW, Roger John; SORCEK, Ronald John; TAKAHASHI, Hidenori; TAYLOR, Steven John; TURNER, Michael Robert; YOUNG, Erick Richard Roush; ZHANG, Qiang; ZHANG, Yunlong; ZINDELL, Renee M.
Patent: WO2014/14874 A1, 2014 ;
Location in patent: Page/Page column 201; 202 ;

84249-14-94-溴吡啶-2-胺

1186115-39-84-溴-5-碘吡啶-2-胺

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2009/147440 A1, 2009 ;
Location in patent: Page/Page column 55-56 ;
WO 2009/147440 A1

84249-14-94-溴吡啶-2-胺

1220220-21-2N-(4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡啶-2-基)乙酰胺

参考文献

US2013/165464 A1, ;

84249-14-94-溴吡啶-2-胺+

33142-21-1(氯甲酰基)乙酸乙酯

1134327-98-27-溴-咪唑并[1,2-a]吡啶-3-羧酸乙酯

参考文献

IRM LLC; TULLY, David C.; RUCKER, Paul Vincent; ALPER, Phillip B.; MUTNICK, Daniel; CHIANELLI, Donatella
Patent: WO2012/87519 A1, 2012 ;
Location in patent: Page/Page column 112 ;
WO 2012/087519 A1