4-甲基-5-氧代-2H-恶唑-3-羧酸乙酯合成路线 （共 2 条）
反应条件
hydroxylamine hydrochloride in ethanol
12 h; Reflux;
参考文献
SCHERING CORPORATION; HARRIS, Joel, M.; STAMFORD, Andrew; GREENLEE, William, J.; NEELAMKAVIL, Santhosh, Francis
Patent: WO2011/53688 A1, 2011 ;
Location in patent: Page/Page column 68 ;
反应条件
1.1: triethylamine; phosphorus oxytribromide / -20 - 80 °C
2.1: sodium tetrahydroborate; methanol / tetrahydrofuran / -20 - 20 °C
2.2: 10 °C / pH 4 - 5
View Scheme
参考文献
SCHERING CORPORATION; HARRIS, Joel, M.; STAMFORD, Andrew; GREENLEE, William, J.; NEELAMKAVIL, Santhosh, Francis
Patent: WO2011/53688 A1, 2011 ;
