4-(3,4-二氟苯基)-4-氧代丁酸合成路线 （共 2 条）
反应条件
AlCl3, aluminium chloride
T=40°C; Friedel-Crafts Acylation; 16 h;
参考文献
LEK PHARMACEUTICALS D.D.; STERK, Damjan; ZUPANCIC, Borut
Patent: WO2013/124280 A1, 2013 ;
Location in patent: Page/Page column 15 ;
反应条件
1: 24 h / Heating
2: H2NNH2, AcOH / H2O / 2 h / Heating
View Scheme
参考文献
Goeschke, R; Gainer, J; Howarth, GA; Wallis, RB; Kerry, R; et al.
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 7 p. 715 - 721
