6-氨基-N-[(1-乙基吡咯烷-2-基)甲基]-4-甲氧基-吡啶-3-甲酰胺合成路线 （共 3 条）
反应条件
ammonia; sodium; ammonium chloride; iron nitrate (III)
1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.;
参考文献
Dostert; Imbert; Ancher; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
反应条件
1: 33 percent / H2O / 12 h / Ambient temperature
2: 45 percent / 1.) liquid NH3, Na, Fe(NO3)3; 2.) NH4Cl / 1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.
View Scheme
参考文献
Dostert; Imbert; Ancher; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
反应条件
1: 33 percent / H2O / 12 h / Ambient temperature
2: 45 percent / 1.) liquid NH3, Na, Fe(NO3)3; 2.) NH4Cl / 1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.
View Scheme
参考文献
Dostert; Imbert; Ancher; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
