顺-N-(4-氯丁烯基)邻苯二甲酰亚胺合成路线 （共 3 条）
反应条件
1: 1.) NaH / 1.) DMF, 2 h, 2.) DMF, 100 deg C, 8 h 2: 1.) hydrazine hydrate, 2.) 4 N aq. HCl / 1.) EtOH, reflux, 8 h, 2.) EtOH, reflux, 6 h View Scheme
参考文献
Wright Jr.; Press; Chan; Marsico; Haug; Lucas; Tauber; Tomcufcik
Journal of Medicinal Chemistry, 1986 , vol. 29, # 4 p. 523 - 530
反应条件
in N,N-dimethyl-formamide
T=20°C; Inert atmosphere;
参考文献
Worthy, Amanda D.; Joe, Candice L.; Lightburn, Thomas E.; Tan, Kian L.
Journal of the American Chemical Society, 2010 , vol. 132, # 42 p. 14757 - 14759
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
T=20°C;
参考文献
Bojarski, Andrzej J.; Duszynska, Beata; Kolaczkowski, Marcin; Kowalski, Piotr; Kowalska, Teresa
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5863 - 5866
