N-Boc-4-氧代-脯氨酸合成路线

参考文献

Vertex Pharmaceuticals Incorporated
Patent: US2010/272681 A1, 2010 ;

参考文献

Mollica, Adriano; Paradisi, Mario Paglialunga; Varani, Katia; Spisani, Susanna; Lucente, Gino
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2253 - 2265

34893-92-03,5-二氯苯异氰酸酯+

84348-37-8N-Boc-4-氧代-脯氨酸

364072-21-9+

767-64-64-氨基-2,1,3-苯并噻二唑

参考文献

Halazy, Serge; Quattropani, Anna; Scheer, Alexander; Schwarz, Mattias; Thomas, Russell; Baxter, Antony
Patent: US2003/212012 A1, 2003 ;

84348-37-8N-Boc-4-氧代-脯氨酸

74844-91-0N-Boc-反式-4-羟基-L-脯氨酸甲酯

参考文献

Bioorganic and Medicinal Chemistry, , vol. 14, # 7 p. 2253 - 2265

102195-80-2Boc-4-氧代-L-脯氨酸甲酯

参考文献

Halazy, Serge; Quattropani, Anna; Scheer, Alexander; Schwarz, Mattias; Thomas, Russell; Baxter, Antony
Patent: US2003/212012 A1, 2003 ;

84348-37-8N-Boc-4-氧代-脯氨酸+

18107-18-1三甲基硅烷化重氮甲烷

102195-80-2Boc-4-氧代-L-脯氨酸甲酯

参考文献

Wityak, John; Prime, Michael E.; Brookfield, Frederick A.; Courtney, Stephen M.; Erfan, Sayeh; Johnsen, Siw; Johnson, Peter D.; Li, Marie; Marston, Richard W.; Reed, Laura; Vaidya, Darshan; Schaertl, Sabine; Pedret-Dunn, Anna; Beconi, Maria; MacDonald, Douglas; Munoz-Sanjuan, Ignacio; Dominguez, Celia
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 12 p. 1024 - 1028

84348-37-8N-Boc-4-氧代-脯氨酸

74844-91-0N-Boc-反式-4-羟基-L-脯氨酸甲酯

参考文献

Torino, Domenica; Mollica, Adriano; Pinnen, Francesco; Feliciani, Federica; Spisani, Susanna; Lucente, Gino
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 1 p. 251 - 259

84348-37-8N-Boc-4-氧代-脯氨酸

74844-91-0N-Boc-反式-4-羟基-L-脯氨酸甲酯

参考文献

Torino, Domenica; Mollica, Adriano; Pinnen, Francesco; Feliciani, Federica; Spisani, Susanna; Lucente, Gino
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 1 p. 251 - 259

84348-37-8N-Boc-4-氧代-脯氨酸

121148-00-3N-Boc-反式-4-氨基-L-脯氨酸甲酯

参考文献

Torino, Domenica; Mollica, Adriano; Pinnen, Francesco; Feliciani, Federica; Spisani, Susanna; Lucente, Gino
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 1 p. 251 - 259

84348-37-8N-Boc-4-氧代-脯氨酸

13726-69-7Boc-L-羟脯氨酸

参考文献

Baldwin, Jack E.; Field, Robert A.; Lawrence, Christopher C.; Merritt, Kirsten D.; Schofield, Christopher J.
Tetrahedron Letters, 1993 , vol. 34, # 46 p. 7489 - 7492