4,4-二甲基-2-(4'-甲基-2-联苯基)-2-噁吖啉合成路线 （共 25 条）
反应条件
in tetrahydrofuran
T=20°C; 2 h; Yield given;
参考文献
Carini, David J.; Duncia, John V.; Aldrich, Paul E.; Chiu, Andrew T.; Johnson, Alexander L.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2525 - 2547
反应条件
in diethyl ether
0.25 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
in diethyl ether
1 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
in diethyl ether
18 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
1: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
2: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
3: 1.) sodium methoxide / 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h
View Scheme
参考文献
Carini, David J.; Duncia, John V.; Aldrich, Paul E.; Chiu, Andrew T.; Johnson, Alexander L.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2525 - 2547
