2-苯甲酰基-1-氰基-1,2-二氢异喹啉合成路线 (共 61 条)
反应条件
in water 24 h; other solvent, or trimethylsilyl cyanide; Product distribution;
参考文献
Duarte, F. F.; Popp, F. D.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1801 - 1804
参考文献
Chemische Berichte, , vol. 38, p. 3432
反应条件
1: aqueous H2SO4 2: platinum; acetic acid / Hydrogenation View Scheme
参考文献
Solomon
Journal of the Chemical Society, 1947 , p. 129
参考文献
Kaufmann; Daendliker
Chemische Berichte, 1913 , vol. 46, p. 2927
参考文献
Reissert
Chemische Berichte, 1905 , vol. 38, p. 3432
反应条件
1: With sodium hydride in N,N-dimethyl-formamide T=-10°C; 1 h; 2: With sodium hydroxide; ethanol; water 0.25 h; Heating / reflux;
参考文献
UNIVERSITE DE LIEGE
Patent: US2009/93517 A1, 2009 ;
Location in patent: Page/Page column 7 ;
US 20090093517 A1
反应条件
sodium hydroxide in methanol 1 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 32, # 10 p. 3900 - 3905
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Australian Journal of Chemistry, , vol. 34, # 1 p. 151 - 162
反应条件
1: diethyl ether; benzene / anschliessendes Erwaermen mit <2-Chlor-aethyl>-dimethyl-amin und Erwaermen des Reaktionsprodukts mit wss.-aethanol. KOH 2: potassium hydroxide; <2>naphthyl-phenyl-amine / unter vermindertem Druck 3: platinum; ethanol / Hydrogenation View Scheme
参考文献
Boekelheide; Sieg
Journal of Organic Chemistry, 1954 , vol. 19, p. 587,591
反应条件
1: NaH / dimethylformamide / 1.)0 deg C, 1 h 2.)r.t., 40 min 2: 40percent aq. KOH / ethanol / 3.5 h / Heating View Scheme
参考文献
Popp; Kant
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 3 p. 869 - 872