2-(4-氨基-1H-吡唑-1-基)乙醇合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate
T=20°C;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED; TAKEDA SAN DIEGO, INC.
Patent: WO2008/156757 A1, 2008 ;
Location in patent: Page/Page column 234 ;
WO 2008/156757 A1
反应条件
sodium ethanolate in ethanol; water
T=5°C; 18 h; Heating / reflux;
参考文献
FUJISAWA PHARMACEUTICAL CO., LTD.; DAISO CO., LTD.
Patent: WO2004/39795 A2, 2004 ;
Location in patent: Page 171-172 ;
WO 2004/039795 A2
反应条件
potassium carbonate in water
参考文献
Imperial Chemical Industries PLC
Patent: US4447441 A1, 1984 ;
US 4447441 A
反应条件
1: hydrogenchloride; water / ethanol / 20 °C
2: hydrogen / palladium 10 on activated carbon / ethanol / 1 h / 20 °C / 2585.81 Torr / Parr shaker bottle
View Scheme
参考文献
Berthel, Steven Joseph; Kester, Robert Francis; Orzechowski, Lucja
Patent: US2012/283271 A1, 2012 ;
US 20120283271 A1
