4-[2-哌啶-1-乙氧基]苯甲酸盐酸盐合成路线 (共 18 条)
反应条件
potassium carbonate in isopropanol acetate; water
参考文献
Eli Lilly and Company
Patent: US5631369 A1, 1997 ;
反应条件
potassium carbonate in isopropanol acetate; water
参考文献
Eli Lilly and Company
Patent: US5631369 A1, 1997 ;
反应条件
1: With sodium hydroxide in methanol; water T=40°C; 4.5 h; 2: With hydrogenchloride in methanol; water
参考文献
Eli Lilly and Company
Patent: US6372945 B1, 2002 ;
Location in patent: Page column 16 ;
反应条件
potassium carbonate in dichloromethane; anhydrous amyl acetate; acetone
反应条件
thionyl chloride; potassium carbonate in dichloromethane; water; acetone
反应条件
potassium carbonate in water; ethyl acetate
反应条件
hydrogenchloride; potassium carbonate in water
参考文献
Eli Lilly and Company
Patent: US5631369 A1, 1997 ;
反应条件
potassium carbonate in dichloromethane; acetone
反应条件
hydrogenchloride; sodium hydroxide in ethanol 2 h; Heating;
参考文献
European Journal of Medicinal Chemistry, , vol. 42, # 1 p. 71 - 80
反应条件
1: potassium carbonate / acetone / Heating 2: aq. sodium hydroxide; HCl / ethanol / 2 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 42, # 1 p. 71 - 80