反应条件
1: 80.4 percent / KOH / ethanol; H2O; ethyl acetate / Ambient temperature 2: 69 percent / PPA / 1 h / 85 - 90 °C 3: 71 percent / pyridine hydrochloride / 6 h / 220 °C 4: 99 percent / 4-(dimethylamino)pyridine, pyridine / Ambient temperature 5: 93 percent / trifluoromethanesulfonic acid / 1,2-dichloro-ethane / Heating 6: 42 percent / 5 N aq. NaOH / ethanol / 1.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 8 p. 1057 - 1066
