3-(4-溴苯基)-4-羟基-6-氧代-6,7-二氢噻吩并[2,3-b]吡啶-5-甲腈合成路线 （共 3 条）
反应条件
sodium hydride in tetrahydrofuran
Heating;
参考文献
Zhao, Gang; Iyengar, Rajesh R.; Judd, Andrew S.; Cool, Barbara; Chiou, William; Kifle, Lemma; Frevert, Ernst; Sham, Hing; Kym, Philip R.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3254 - 3257
反应条件
1: 90 percent / PCl5; Et3N / CH2Cl2
2: 80 percent / NaH / tetrahydrofuran / Heating
View Scheme
参考文献
Zhao, Gang; Iyengar, Rajesh R.; Judd, Andrew S.; Cool, Barbara; Chiou, William; Kifle, Lemma; Frevert, Ernst; Sham, Hing; Kym, Philip R.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3254 - 3257
反应条件
1: S; morpholine / ethanol / 60 °C
2: 90 percent / PCl5; Et3N / CH2Cl2
3: 80 percent / NaH / tetrahydrofuran / Heating
View Scheme
参考文献
Zhao, Gang; Iyengar, Rajesh R.; Judd, Andrew S.; Cool, Barbara; Chiou, William; Kifle, Lemma; Frevert, Ernst; Sham, Hing; Kym, Philip R.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3254 - 3257
