N-丁基-β-咔啉-3-羧酸酯合成路线 （共 4 条）
反应条件
1: With sodium hydroxide; thionyl chloride
6 h; Heating / reflux;
2: With sodium hydrogencarbonate in water; ethyl acetate
pH=8;
参考文献
Xinjiang Huashidan Pharmaceutical Research Co., Ltd.
Patent: EP1634881 A1, 2006 ;
Location in patent: Page/Page column 18; 19; 95 ;
反应条件
chloranil in various solvent(s)
1.5 h; Heating;
参考文献
Lippke; Schunack; Wenning; Muller
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 499 - 503
反应条件
1: 97 percent / NaOH / H2O / 3 h / Heating
2: 50 percent / HCl (gas)
3: 30 percent / chloranil / various solvent(s) / 1.5 h / Heating
View Scheme
参考文献
Lippke; Schunack; Wenning; Muller
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 499 - 503
反应条件
1: 50 percent / HCl (gas)
2: 30 percent / chloranil / various solvent(s) / 1.5 h / Heating
View Scheme
参考文献
Lippke; Schunack; Wenning; Muller
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 499 - 503
