3-叠氮基-2,3-二脱氧尿苷合成路线 （共 23 条）
反应条件
1: 1.) Br2, 2.) air, 3.) triethylamine / 1.) H2O, THF, room temperature, 3.) room temperature
2: 1 N NaOH / methanol; H2O / 48 h / Ambient temperature
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参考文献
Lin, Tai-Shun; Guo, Ji-Yu; Schinazi, Raymond F.; Chu, Chung K.; Xiang, Jia-Ning; Prusoff, Willian H.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 336 - 340
参考文献
Lin; Mancini
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 544 - 548
反应条件
methanol; ammonium sulfate; formamide; 1,1,1,3,3,3-hexamethyl-disilazane
1.) 120 deg C, 71 h, 2.) reflux, 6 h; Multistep reaction;
参考文献
Lin; Mancini
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 544 - 548
