1-(5-异喹啉磺酰基)-2-甲基哌嗪合成路线 （共 4 条）
参考文献
Asahi Kasei Kogyo Kabushiki Kaisha; Hidaka; Hiroyoshi
Patent: US4456757 A1, 1984 ;
反应条件
hydrogen bromide in acetic acid
参考文献
Morikawa; Sone; Asano
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773
反应条件
1: Et3N / CHCl3 / 4 h / Ambient temperature
2: 1.) H2O, NaHCO3, 2.) Et3N / 2.) CH2Cl2, RT, overnight
3: 25percent HBr / acetic acid
View Scheme
参考文献
Morikawa; Sone; Asano
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773
反应条件
1: 1.) H2O, NaHCO3, 2.) Et3N / 2.) CH2Cl2, RT, overnight
2: 25percent HBr / acetic acid
View Scheme
参考文献
Morikawa; Sone; Asano
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773
