4-甲氧基-3-硝基吡啶-2-胺合成路线 （共 8 条）
反应条件
1: T=60°C; 16 h; 2: With hydrogenchloride in water pH=6;
参考文献
H. LUNDBECK A/S; JØRGENSEN, Morten; BRUUN, Anne Techau; RASMUSSEN, Lars Kyhn
Patent: WO2013/34761 A1, 2013 ;
Location in patent: Page/Page column 19 ;
反应条件
sulfuric acid T=0 - 20°C;
参考文献
Deady, Leslie W.; Korytsky, Olga L.; Rowe, Jeffrey E.
Australian Journal of Chemistry, 1982 , vol. 35, # 10 p. 2025 - 2034
反应条件
sodium 2 h; Heating;
参考文献
Barraclough; Black; Cambridge; Collard; Firmin; Gerskowitch; Glen; Giles; Hill; Hull; Iyer; King; Kneen; Lindon; Nobbs; Randall; Shah; Smith; Vine; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2231 - 2239
反应条件
1: 44 percent / methanol / 7 h / 140 °C 2: concd. H2SO4, fuming HNO3 / 0.33 h / 0 °C 3: 93 percent / concd. H2SO4 / 0 - 20 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
1: diphenylphosphoryl azide, triethylamine / 26 h / Heating 2: 25percent HBr / 2 h / Ambient temperature 3: 44 percent / methanol / 7 h / 140 °C 4: concd. H2SO4, fuming HNO3 / 0.33 h / 0 °C 5: 93 percent / concd. H2SO4 / 0 - 20 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
1: 25percent HBr / 2 h / Ambient temperature 2: 44 percent / methanol / 7 h / 140 °C 3: concd. H2SO4, fuming HNO3 / 0.33 h / 0 °C 4: 93 percent / concd. H2SO4 / 0 - 20 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
1: concd. H2SO4, fuming HNO3 / 0.33 h / 0 °C 2: 93 percent / concd. H2SO4 / 0 - 20 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
sulfuric acid; potassium nitrate T=30°C; other 4-substituted 2-nitraminopyridines; Rate constantMechanism;
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2035 - 2040
