(2S,4S)-1-叔丁基二甲基4-氨基吡咯烷-1,2二羧酸合成路线 （共 4 条）
参考文献
Erdmann, Roman S.; Wennemers, Helma
Angewandte Chemie - International Edition, 2011 , vol. 50, # 30 p. 6835 - 6838
反应条件
hydrogen; palladium on activated charcoal in 1,4-dioxane 24 h;
参考文献
LG LIFE SCIENCES LTD.
Patent: WO2010/56022 A2, 2010 ;
Location in patent: Page/Page column 22 ;
WO 2010/056022 A2
反应条件
water; triphenylphosphine in tetrahydrofuran 6 h; Reflux;
参考文献
Han, Bo; Knust, Henner; Nettekoven, Matthias; Ratni, Hasane; Wu, Xihan
Patent: US2008/306086 A1, 2008 ;
Location in patent: Page/Page column 11-12; 28 ;
US 20080306086 A1
反应条件
1: 2N NaOH / dioxane / 1 h / 25 °C
2: conc. HCl / dioxane / 2 h / 50 °C / pH 2
View Scheme
参考文献
Le Quement, Sebastian T.; Ishoey, Mette; Petersen, Mette T.; Thastrup, Jacob; Hagel, Grith; Nielsen, Thomas E.
ACS Combinatorial Science, 2011 , vol. 13, # 6 p. 667 - 675
