5-(氯甲基)-1-甲基-1H-吡唑合成路线 (共 2 条)
反应条件
thionyl chloride in dichloromethane
T=20°C; 2 h;
参考文献
BIOENERGENIX; MCCALL, John; KELLY, Robert, C.; ROMERO, Donna, L.
Patent: WO2014/66795 A1, 2014 ;
Location in patent: Paragraph 0175 ;
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C / |Inert atmosphere
2: thionyl chloride / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
BIOENERGENIX; MCCALL, John; KELLY, Robert, C.; ROMERO, Donna, L.
Patent: WO2014/66795 A1, 2014 ;