5-氟-2,3-二氢苯并[d]异噻唑1,1-二氧化物合成路线 （共 5 条）
反应条件
ammonia in tetrahydrofuran; water
1 h;
参考文献
ATHERSYS, INC.
Patent: WO2006/34419 A2, 2006 ;
Location in patent: Page/Page column 64-65 ;
WO 2006/034419 A2
反应条件
hydrogenchloride; zinc in ethanol
T=25°C; 2 h;
参考文献
Pal, Manojit; Veeramaneni, Venugopal Rao; Kumar, Sanjeev; Lohray, Vidya B.; Yeleswarapu, Koteswar Rao
Journal of the Indian Chemical Society, 2003 , vol. 80, # 12 p. 1095 - 1101
反应条件
1: 75 percent / chlorosulfonic acid / 0 °C
2: 79 percent / aq. NH3 / dioxane / 6 h / 0 °C
3: 46 percent / aq. NaOH; KMnO4 / 6 h
4: 33 percent / HCl; Zn / ethanol / 2 h / 25 °C
View Scheme
参考文献
Pal, Manojit; Veeramaneni, Venugopal Rao; Kumar, Sanjeev; Lohray, Vidya B.; Yeleswarapu, Koteswar Rao
Journal of the Indian Chemical Society, 2003 , vol. 80, # 12 p. 1095 - 1101
反应条件
1: 46 percent / aq. NaOH; KMnO4 / 6 h
2: 33 percent / HCl; Zn / ethanol / 2 h / 25 °C
View Scheme
参考文献
Pal, Manojit; Veeramaneni, Venugopal Rao; Kumar, Sanjeev; Lohray, Vidya B.; Yeleswarapu, Koteswar Rao
Journal of the Indian Chemical Society, 2003 , vol. 80, # 12 p. 1095 - 1101
反应条件
1: 79 percent / aq. NH3 / dioxane / 6 h / 0 °C
2: 46 percent / aq. NaOH; KMnO4 / 6 h
3: 33 percent / HCl; Zn / ethanol / 2 h / 25 °C
View Scheme
参考文献
Pal, Manojit; Veeramaneni, Venugopal Rao; Kumar, Sanjeev; Lohray, Vidya B.; Yeleswarapu, Koteswar Rao
Journal of the Indian Chemical Society, 2003 , vol. 80, # 12 p. 1095 - 1101
