4-[(4-溴苄基)氨基]-1-哌啶羧酸叔丁酯合成路线 (共 1 条)
反应条件
1: With N-ethyl-N,N-diisopropylamine in methanol
4 h; Heating / reflux;
2: With sodium tetrahydroborate in methanol
T=20°C; 0.25 h; Product distribution / selectivity;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2005/58822 A1, 2005 ;
Location in patent: Page/Page column 20-21; 26 ;