2-氯-1-氟-4-(甲基磺酰基)苯合成路线 (共 2 条)
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=0 - 10°C; 0.25 h;
2: With hydrogenchloride; copper(l) chloride in water
T=0 - 40°C; 0.166667 h;
参考文献
ARGENTA DISCOVERY LTD.
Patent: WO2007/31747 A1, 2007 ;
Location in patent: Page/Page column 54 ;
WO 2007/031747 A1
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
T=20°C; 2 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/5909 A1, 2006 ;
Location in patent: Page/Page column 33 ;
WO 2006/005909 A1