(R)-1-(3,4-二氟苯基)-1-丙胺盐酸盐合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Van Lommen, Guy; Doyon, Julien; Coesemans, Erwin; Boeckx, Staf; Cools, Marina; Buntinx, Mieke; Hermans, Bart; VanWauwe, Jean
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 497 - 500
反应条件
1: 100 percent / Ti(i-PropO)4; 1R,2R-1,2-di(CF3SO2NH)-cyclohexane / toluene / -78 °C
2: 75 percent / diphenylphosphorylazide; DBU / toluene
3: 75 percent / H2 / Pd/C / methanol
View Scheme
参考文献
Van Lommen, Guy; Doyon, Julien; Coesemans, Erwin; Boeckx, Staf; Cools, Marina; Buntinx, Mieke; Hermans, Bart; VanWauwe, Jean
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 497 - 500
反应条件
1: 75 percent / diphenylphosphorylazide; DBU / toluene
2: 75 percent / H2 / Pd/C / methanol
View Scheme
参考文献
Van Lommen, Guy; Doyon, Julien; Coesemans, Erwin; Boeckx, Staf; Cools, Marina; Buntinx, Mieke; Hermans, Bart; VanWauwe, Jean
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 497 - 500
