1: With sodium t-butanolate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2-dicyclohexylphosphino-1,1'-biphenyl in toluene
T=80°C; 16 h;
2: With Isolute HM-N in toluene
T=20°C;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2005/23260 A1, 2005 ;
Location in patent: Page/Page column 43; 44 ;
WO 2005/023260 A1