N-(4-氧代丁基)氨基甲酸叔丁酯合成路线 （共 3 条）
反应条件
[Rh(acac)2(CO)2]; C50H44Cl4N4O4P2; hydrogen in toluene
T=60°C; P=15001.5 Torr; 20 h; Inert atmosphereAutoclave; enantioselective reaction;
参考文献
Xu, Kun; Zheng, Xin; Wang, Zhiyong; Zhang, Xumu
Chemistry - A European Journal, 2014 , vol. 20, # 15 p. 4357 - 4362
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine
1.) CH2Cl2, -70 deg C, 15 min, 2.) a) -70 deg C, 5 min, b) -70 deg C to room temperature; Yield given. Multistep reaction;
参考文献
Ferraccioli; Dalla Croce; Gallina; Consalvi; Scandurra
Farmaco, 1991 , vol. 46, # 12 p. 1517 - 1529
反应条件
1: 90 percent / tetrahydrofuran / 12 h / 25 °C
2: 1.) DMSO, (COCl)2, 2.) Et3N / 1.) CH2Cl2, -70 deg C, 15 min, 2.) a) -70 deg C, 5 min, b) -70 deg C to room temperature
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参考文献
Ferraccioli; Dalla Croce; Gallina; Consalvi; Scandurra
Farmaco, 1991 , vol. 46, # 12 p. 1517 - 1529
