1: With boron tribromide in dichloromethane
T=0°C; 1 h;
2: With ammonia in dichloromethane; water
pH=9; 1 h;
3: With hydrogenchloride in dichloromethane; water
pH=~ 2;
参考文献
PFIZER INC.
Patent: WO2005/21553 A1, 2005 ;
Location in patent: Page/Page column 45 ;
WO 2005/021553 A1