(S)-N-Boc-2-吗啉甲醛合成路线 （共 6 条）
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; trichloroisocyanuric acid; sodium hydrogencarbonate in ethyl acetate T=-5°C; 2 h;
参考文献
MOLECULAR NEUROIMAGING, LLC
Patent: WO2007/5935 A2, 2007 ;
Location in patent: Page/Page column 52; 53 ;
WO 2007/005935 A2
反应条件
1: NaOH 2: trichloroisocyanuric acid; TEMPO; NaHCO3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 2 p. 533 - 537
反应条件
1: red-Al / tetrahydrofuran 2: NaOH 3: trichloroisocyanuric acid; TEMPO; NaHCO3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 2 p. 533 - 537
反应条件
1: t-BuOK / 2-methyl-butan-2-ol 2: red-Al / tetrahydrofuran 3: NaOH 4: trichloroisocyanuric acid; TEMPO; NaHCO3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 2 p. 533 - 537
反应条件
1: 83 percent / NaOH / CH2Cl2; H2O / 3 h / 20 °C 2: 89 percent / TEMPO; NaHCO3; trichloroisocyanuric acid / ethyl acetate / 2 h / -5 °C View Scheme
参考文献
Organic Letters, , vol. 7, # 5 p. 937 - 939
反应条件
1: diborane / tetrahydrofuran / 2.5 h / |Reflux 2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / 1,2-dichloro-ethane / 18 h / 70 °C View Scheme
