7-(哌嗪-1-基)-1H-吲哚合成路线 （共 4 条）
反应条件
hydrogenchloride; potassium carbonate in butan-1-ol
参考文献
John Wyeth and Brother, Ltd.
Patent: US5627177 A1, 1997 ;
反应条件
1: Fe, aq. HCl / ethanol
2: p-TsOH / chlorobenzene
View Scheme
参考文献
Kuipers, Wilma; Wijngaarden, Ineke van; Kruse, Chris G.; Amstel, Marian ter Horst-van; Tulp, Martin Th. M.; IJzerman, Adriaan P.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1942 - 1954
反应条件
toluene-4-sulfonic acid in chlorobenzene
参考文献
Kuipers, Wilma; Wijngaarden, Ineke van; Kruse, Chris G.; Amstel, Marian ter Horst-van; Tulp, Martin Th. M.; IJzerman, Adriaan P.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1942 - 1954
反应条件
trifluoroacetic acid
参考文献
Fisher, Matthew J.; Backer, Ryan T.; Husain, Saba; Hsiung, Hansen M.; Mullaney, Jeffrey T.; O'Brian, Thomas P.; Ornstein, Paul L.; Rothhaar, Roger R.; Zgombick, John M.; Briner, Karin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4459 - 4462
