2-(烯丙氧基甲基)-18-冠-6-醚合成路线 （共 8 条）
反应条件
perchloric acid; palladium on activated charcoal in ethanol T=80°C; 24 h;
参考文献
Ikeda, Isao; Emura, Hiroshi; Okahara, Mitsuo
Synthesis, 1984 , # 1 p. 73 - 74
反应条件
potassium hydroxide in 1,4-dioxane
T=80°C; 18 h;
参考文献
Belohradsky, Martin; Stibor, Ivan; Holy, Petr; Zavada, Jiri
Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 10 p. 2500 - 2507
反应条件
potassium hydroxide in tetrahydrofuran
2 h; Heating;
参考文献
Buschbeck, Roy; Lang, Heinrich
Journal of Organometallic Chemistry, 2005 , vol. 690, # 3 p. 696 - 703
反应条件
KClO4; sodium hydride in tetrahydrofuran
参考文献
Favre-Reguillon, Alain; Dumont, Nathalie; Dunjic, Branko; Lemaire, Marc
Tetrahedron Letters, 1995 , vol. 36, # 36 p. 6439 - 6442
反应条件
KClO4; sodium hydride in tetrahydrofuran
24 h; Heating;
参考文献
Favre-Reguillon, Alain; Dumont, Nathalie; Dunjic, Branko; Lemaire, Marc
Tetrahedron, 1997 , vol. 53, # 4 p. 1343 - 1360
反应条件
1: 87.3 percent / NaH / dioxane; paraffin / 1.) 2.5h, reflux, 2.) 24h, reflux
2: KH / tetrahydrofuran / 1.) 3h, 2.) 15h, RT; 24h, reflux
View Scheme
参考文献
Jungk, Steven John; Moore, Jane Ann; Gandour, Richard David
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1116 - 1120
反应条件
potassium hydride in tetrahydrofuran
1.) 3h, 2.) 15h, RT; 24h, reflux;
参考文献
Jungk, Steven John; Moore, Jane Ann; Gandour, Richard David
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1116 - 1120
反应条件
potassium hydroxide; p-toluenesulfonyl chloride
1.) 1 h, 80 deg C, 2.) dioxan, 4 h, reflux; Yield given. Multistep reaction;
参考文献
Ikeda, Isao; Emura, Hiroshi; Okahara, Mitsuo
Synthesis, 1984 , # 1 p. 73 - 74
